BIOPHARMACEUTICS & PHARMACOKINETICS MADAN PDF

As defmed in Chapter I, the study of pharmacokinetics involves the application of principles of kinetics. The principles of kinetics, in most cases, involve rather extensive use of logarithms, as well as construction of graphs with the data in order to obtain a clear and comprehensive picture of the data. Even in a tabular form, the raw data do not present a clear picture. When it is very difficult to comprehend raw data, any conclusions drawn from the raw data are a gross approximation at best. In constructing graphs, an effort is made to obtain a linear relationship between the variables. If it is not possible to obtain a straight line, one may settle for a smooth curve, because even a smooth curve permits a much better understanding of relationship between the variables than looking at raw data in a tabular form.

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Biopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book along with the fundamentals of absorption distribution metabolism and excretion current topics such as in vitro systems have also been introduced.

In case of Pharmacokinetic Models authors have tried to keep mathematical part simpler and minimal. This book also introduces Non-compartmental models which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter Applications of Pharmacokinetics newer concepts such as chronopharmacokinetics have been introduced.

Bioequivalence is covered in last two chapters. Besides clinical aspect of bioequivalence some of the important aspects of bioanalysis have also been introduced. The regulatory aspect of bioequivalence has also been covered.

Thus an attempt has been made to cover all the basic aspects of biopharmaceutics and pharmacokinetics in a reader-friendly manner. About the Author Jayant S. Kulkarni Ph. He has published 14 research articles in international and has presented his research work at various international national conferences. Atmaram P. Pawar Ph. University of Pune has more teaching experience. He has presented his research at various international and national conferences.

Shedbalkar Ph. He has co-authored 25 research articles in national and international journals. Explore Plus. Higher Education and Professional Books. Medical and Nursing Books. Biopharmaceutics and Pharmacokinetics English, Hardcover, unknown.

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Jaypee Biopharmaceutics and Pharmacokinetics by PL Madan for Medical Pharmacology 2 Edition 2014

Biopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book along with the fundamentals of absorption distribution metabolism and excretion current topics such as in vitro systems have also been introduced. In case of Pharmacokinetic Models authors have tried to keep mathematical part simpler and minimal. This book also introduces Non-compartmental models which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter Applications of Pharmacokinetics newer concepts such as chronopharmacokinetics have been introduced. Bioequivalence is covered in last two chapters.

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Biopharmaceutics and Pharmacokinetics P.L.Madan.pdf

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